HCID 68815838, compound → HCID 68816510, compound

HRID 735189Notes

Reaction equation

HRID 735189 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[N:10]=[C:9]([CH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][NH:15]1)[CH:8]=[CH:7]2)([O-])=O>ClCCl.CO>[NH2:1][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[N:10]=[C:9]([CH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][NH:15]1)[CH:8]=[CH:7]2

Participants

3

Reactant 1

HCID 68815838HCID 68815838, compound

Product 1

HCID 68816510HCID 68816510, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

Prepared analogously to Example 3.1.b. from 6-nitro-2-piperidin-2-yl-quinoline. Yield: 0.79 g (59.6% of theory); C14H17N3 (M=227.31); calc.: molecular ion peak (M+H)+: 228; found: molecular ion peak (M+H)+: 228; Rf value: 0.37 (silica gel, dichloromethane/methanol (19:1)).

Workup

  1. customPrepared analogously to Example 3.1.b

Sources & evidence

ORD record
ord-053d54b6332c48918a0340a73d9c23b1
Source dataset
uspto-grants-2009_09
Patent number
US07592373B2

Reaction notes

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