HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl morpholine oxide → 1-[(1R)-4-Methylcyclohex-3-en-1-yl]-propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl morpholine oxide | HCID 82029 | — |
| Reactant | (1R)-4-methylcyclohex-3-ene-1-carbaldehyde | HCID 7367165 | — |
| Reactant | HCID 178418443 | HCID 178418443 | — |
| Catalyst | HCID 178419074 | HCID 178419074 | — |
| Product | 1-[(1R)-4-Methylcyclohex-3-en-1-yl]-propan-1-one | HCID 57847651 | — |
Reaction Steps
(1R)-4-Methyl-3-cyclohexene-1-carboxaldehyde was treated with ethylmagnesium bromide followed by tetrapropylammonium perruthenate and 4-methylmorpholine N-oxide to afford 1-[(1R)-4-methylcyclohex-3-en-1-yl]-propan-1-one; [α]D=+41.3 (c=1.0, CHCl3). The product was identical in all respects to the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592463B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-83f253b03cf44160a001debe0d542819 |
| Source note | uspto-grants-2009_09 |