Sodium Hydroxide → HCID 10479919, compound

HRID 735383Notes

Reaction equation

HRID 735383 reaction equation
[CH3:1][C:2]1([CH3:33])[C:11]2[CH:10]=[C:9]([Se:12][C:13]#[C:14][C:15]3[CH:25]=[CH:24][C:18]([C:19]([O:21]CC)=[O:20])=[CH:17][N:16]=3)[CH:8]=[CH:7][C:6]=2[C:5]([C:26]2[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][CH:27]=2)=[CH:4][CH2:3]1.[OH-].[Na+]>>[CH3:1][C:2]1([CH3:33])[C:11]2[CH:10]=[C:9]([Se:12][C:13]#[C:14][C:15]3[CH:25]=[CH:24][C:18]([C:19]([OH:21])=[O:20])=[CH:17][N:16]=3)[CH:8]=[CH:7][C:6]=2[C:5]([C:26]2[CH:27]=[CH:28][C:29]([CH3:32])=[CH:30][CH:31]=2)=[CH:4][CH2:3]1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 86601148HCID 86601148, compound

Product 1

HCID 10479919HCID 10479919, compound

Procedure

In a manner similar to that of Example 7d, by reacting 0.9 g (1.8 mmol) of ethyl 6-(8,8-dimethyl-5-p-tolyl-7,8-dihydro-2-naphthylselanylethynyl)nicotinate with 0.36 g (9 mmol) of sodium hydroxide, a yellow solid is obtained (0.60 g; yield=71%; m.p.=171° C.).

Workup

  1. customa yellow solid is obtained (0.60 g; yield=71%; m.p.=171° C.)

Sources & evidence

ORD record
ord-6719e24673df4614bc96a380de98c19d
Source dataset
uspto-grants-2009_09
Patent number
US07592478B2

Reaction notes

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