反应详情

2 g (4.7 mmol) of 4-[3-(8,8-dimethyl-5-p-tolyl-7,8-dihydro-2-naphthyl)-3-oxopropenyl]benzoic acid are dissolved in 50 ml of methanol, and 2.1 g (5.6 mmol) of caesium chloride are then added. After 30 minutes, 0.18 g (4.8 mmol) of sodium borohydride is added. After 30 minutes, the medium is treated with ammonium chloride solution and extracted with ethyl acetate. The residue obtained is purified by chromatography (eluent: 50/50 heptane/ethyl acetate). A solid is obtained (0.42 g; yield=21%; m.p. >300° C., dec).

1. waitAfter 30 minutes
2. extractionextracted with ethyl acetate
3. customThe residue obtained
4. customis purified by chromatography (eluent: 50/50 heptane/ethyl acetate)
5. customA solid is obtained (0.42 g; yield=21%; m.p. >300° C., dec)