Thionyl Chloride → HCID 67021058, compound

Participants

Reaction Steps

2-Azido-N-phenyl-3-trifluoromethyl-benzamide (310 mg, 1 mmol, compound of formula (X)) was heated in 2 ml of SOCl2 in a sealed vial at 100° C. for 4 hours. After evaporation of SOCl2 in vacuo the residue was purified by column chromatography on silica (n-heptane/ethyl acetate, 50:50, as eluent). Yield: 212 mg (72%).

Provenance & Evidence