HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 7-chloro-3-(2,4-dimethoxyphenyl)-1H-indazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | (3-Chloro-2-fluorophenyl)(2,4-dimethoxyphenyl)methanone | HCID 64713965 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | 7-chloro-3-(2,4-dimethoxyphenyl)-1H-indazole | HCID 178489141 | 52.2% |
Reaction Steps
Prepared as in Example 104 from (2,4-dimethoxyphenyl)[2-fluoro-3-chlorophenyl]methanone (1.20 g, 4.1 mmol), hydrazine hydrate (1.61 mL, 51.7 mmol) and DMAP (0.632 g, 5.17 mmol) to give the product (0.618 g) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592363B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-7ee351c404a1498892be975dc50bafd1 |
| Source note | uspto-grants-2009_09 |