Cyclohexene → HCID 136358455, compound

HRID 735434Notes

Reaction equation

HRID 735434 reaction equation
[Cl:1][C:2]1[C:10]2[C:6](=[C:7]([C:14]3[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][C:15]=3[CH3:22])[N:8]([CH:11]([CH3:13])[CH3:12])[N:9]=2)[CH:5]=[CH:4][CH:3]=1.B(Br)(Br)Br.C1CCCCC=1>>[Cl:1][C:2]1[C:10]2[C:6](=[C:7]([C:14]3[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=3[CH3:22])[N:8]([CH:11]([CH3:13])[CH3:12])[N:9]=2)[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 67021072HCID 67021072, compound

Product 1

HCID 136358455HCID 136358455, compoundYield 33.2%

Procedure

Prepared according to Example 128 from 7-chloro-2-isopropyl-3-(4-methoxy-2-methylphenyl)-2H-indazole (0.05 g, 0.16 mmol), boron tribromide (0.19 mL, 2.0 mmol) and 1.0 mL of cyclohexene to give the product (0.016 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-7fa71967b27f443c91e082f865d02f5b
Source dataset
uspto-grants-2009_09
Patent number
US07592363B2

Reaction notes

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