Cyclohexene → HCID 135432870, compound

HRID 735435Notes

Reaction equation

HRID 735435 reaction equation
[Cl:1][C:2]1[C:10]2[C:6](=[C:7]([C:14]3[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][C:15]=3[CH3:22])[N:8]([CH2:11][CH2:12][CH3:13])[N:9]=2)[CH:5]=[CH:4][CH:3]=1.B(Br)(Br)Br.C1CCCCC=1>>[Cl:1][C:2]1[C:10]2[C:6](=[C:7]([C:14]3[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=3[CH3:22])[N:8]([CH2:11][CH2:12][CH3:13])[N:9]=2)[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 67021037HCID 67021037, compound

Product 1

HCID 135432870HCID 135432870, compoundYield 58.8%

Procedure

Prepared according to Example 128 from 7-chloro-3-(4-methoxy-2-methylphenyl)-2-propyl-2H-indazole (0.04 g, 0.13 mmol), boron tribromide (0.20 mL, 2.10 mmol) and 1.0 mL of cyclohexene to give the product (0.023 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-553c964ab1b54b3f9c95cf9a6c2c62e3
Source dataset
uspto-grants-2009_09
Patent number
US07592363B2

Reaction notes

Loading…