p-Toluenesulfonic acid → HCID 67021327, compound

Participants

Reaction Conditions

Reaction Steps

Fifty milligrams (50 mg; 0.15 mmol) of 2-(2-benzyl-3-phenyl-2H-indazol-7-yl)propan-2-ol (Example 520) were dissolved in 2 ml of toluene followed by the addition of 11 mg of TsOH. The mixture was heated at 110° C. for 1 hour. After cooling, the resulting solution was filtered through SiO2 plug affording, after evaporation, 45 mg of pure 2-benzyl-7-isopropenyl-3-phenyl-2H-indazole. Yield: 94%.

Provenance & Evidence