HuagongsheHuagongshe Chemistry Print Report · For research reference only
Salicylaldehyde → HCID 86603030, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Salicylaldehyde | HCID 6998 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-Benzyl-3-(3-bromo-phenyl)-7-trifluoromethyl-2H-indazole | HCID 11604414 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 86603030 | HCID 86603030 | — |
Reaction Steps
The preparation of this compound is was similar to that described for Example 3. 2-Benzyl-3-(3-bromo-phenyl)-7-trifluoromethyl-2H-indazole (60 mg, 0.139 mmol), cesium carbonate (272 mg, 0.835 mmol), CuI (80 mg, 0.417 mmol) and 2-hydroxy-benzaldehyde (51 mg, 0.417 mmol) were dissolved in 6 ml of dry pyridine. The reaction and work-up were carried out as described for Example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592363B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-2b324e76535341d3b6842d08d27475c5 |
| Source note | uspto-grants-2009_09 |