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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 735497Generated: October 26, 2026

Benzyl Bromide → HCID 57842557, compound

https://huagongshe.com/reaction/735497

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
Reactant4-(2-Carboxyethyl)benzeneboronic acidHCID 3863484—
ReactantHCID 57842668HCID 57842668—
ProductHCID 57842557HCID 5784255762%

Reaction Steps

Using a procedure analogous to that used to prepare 1B, 3-(4-boronophenyl)propanoic acid (388 mg, 2.00 mmol) was reacted with benzyl bromide to afford 4A (355 mg, 62%) as a white solid. 1H NMR (400 MHz, tetrahydrofuran-d8) δ 2.71 (t, J=7.9 Hz, 2H), 3.02 (t, J=7.5 Hz, 2H), 5.10 (s, 2H), 7.25-7.35 (m, 5H), 8.12 (d, J=7.9 Hz, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592331B2
Source datasetuspto-grants-2009_09
ORD IDord-b05b33c87eb94656aac5645a69fdfe2e
Source noteuspto-grants-2009_09