4-(4-Bromophenyl)-N-(3-cyano-4-(isopropylsulfonyl)phenyl)butanamide → N-(3-Cyano-4-(isopropylsulfonyl)phenyl)-4-(4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl)butanamide

Participants

Reaction Steps

Using a procedure analogous to that used to prepare 2A, 9C (600 mg, 1.34 mmol) was reacted with 5,5′,5′-tetramethyl-[2,2′]bi[[1,3,2]dioxaborinanyl] to give 9D (625 mg, 97%) as a brown foam. MS (ESI) m/z 413.1 (M−H)− for free boronic acid.

Provenance & Evidence