4-(4-Bromophenyl)-N-(4-(tert-butylsulfonyl)-3-cyanophenyl)butanamide → N-(4-(tert-butylsulfonyl)-3-cyanophenyl)-4-(4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl)butanamide

Participants

Reaction Steps

Using a procedure analogous to that used to prepare 2A, 10C (430 mg, 0.930 mmol) was reacted with 5,5′,5′-tetramethyl-[2,2′]bi[[1,3,2]dioxaborinanyl] to give 10D (431 mg, 93%) as a brown foam. This crude material was taken on to the next step.

Provenance & Evidence