HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[4-(5,5-Dimethyl-[1,3,2]dioxaborinan-2-yl)-phenyl]-butyric acid → (3-Cyanophenyl)carbamic acid 2-[4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-phenyl]ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[4-(5,5-Dimethyl-[1,3,2]dioxaborinan-2-yl)-phenyl]-butyric acid | HCID 57842777 | — |
| Reactant | 4-Bromophenethyl 3-cyanophenylcarbamate | HCID 57842826 | — |
| Product | (3-Cyanophenyl)carbamic acid 2-[4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-phenyl]ethyl ester | HCID 57842566 | 76% |
Reaction Steps
Using a procedure analogous to that used to prepare 2A, 11A (516 mg, 1.50 mmol) was reacted with 5,5′,5′-tetramethyl-[2,2′]bi[[1,3,2]dioxaborinanyl] to give 11B (434 mg, 76%). This crude material was taken on to the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-5a0817db0c864938b1ebd96e8c03336b |
| Source note | uspto-grants-2009_09 |