HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boronic Acid → HCID 57842682, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boronic Acid | HCID 61668 | — |
| Reactant | Bis(neopentyl glycolato)diboron | HCID 2734316 | — |
| Reactant | 4-(4-(3-Cyano-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenylboronic acid | HCID 57842684 | — |
| Reactant | tert-Butyl 5-(4-(4-bromophenyl)butanamido)-2-(ethylsulfonyl)benzylcarbamate | HCID 57842758 | — |
| Product | HCID 57842682 | HCID 57842682 | 82% |
Reaction Steps
Using a procedure analogous to that used to prepare 6D, 15B (0.541 g, 1.0 mmol) was coupled to 5,5,5′,5′-tetramethyl-[2,2′]bi[[1,3,2]dioxaborinanyl](0.249 g, 1.1 mmol) and then hydrolyzed to the free boronic acid to give 15C (334 mg, 82%) as a peach colored foam. MS (ESI) m/z 505.03 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-985f94c5ebf848e6b030595cc957d660 |
| Source note | uspto-grants-2009_09 |