HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 2-(4-bromophenyl)-N-methylacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Benzeneacetic acid, 4-bromo- | HCID 74654 | — |
| Reactant | 3-(4-bromophenyl)-N-methylpropanamide | HCID 17895055 | — |
| Product | 2-(4-bromophenyl)-N-methylacetamide | HCID 842546 | 75% |
Reaction Steps
Using a procedure analogous to that used to prepare 22A, 2-(4-bromophenyl)acetic acid (1.6 g, 7.0 mmol) was coupled to methylamine to yield 23A (2.0 g, 75%) as a white solid. MS (ESI) m/z 228.20/230.20 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-41e1d6476d514bb2b58d2b75876faa14 |
| Source note | uspto-grants-2009_09 |