HuagongsheHuagongshe Chemistry Print Report · For research reference only
Borane → 2-(4-Bromophenyl)-N-methylethan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Borane | HCID 6331 | — |
| Reactant | 2-(4-bromophenyl)-N-methylacetamide | HCID 842546 | — |
| Reactant | 3-(4-Bromophenyl)-N-methylpropan-1-amine | HCID 28350540 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(4-Bromophenyl)-N-methylethan-1-amine | HCID 18367556 | 97% |
Reaction Steps
Using a procedure analogous to that used to prepare 22B, 23A (1.6 g, 7.0 mmol) was reduced with borane in THF to yield 23B (1.45 g, 97%) as a clear oil. MS (ESI) m/z 214.22/216.22 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-cd5ad2f2237d4e3087ff50ef31bf2f1f |
| Source note | uspto-grants-2009_09 |