HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glyoxylic acid, monohydrate → HCID 57842902, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glyoxylic acid, monohydrate | HCID 15620607 | — |
| Reactant | tert-butyl N-(6-aminoisoquinolin-1-yl)-N-[(tert-butoxy)carbonyl]carbamate | HCID 58717298 | — |
| Reactant | HCID 68816554 | HCID 68816554 | — |
| Product | HCID 57842902 | HCID 57842902 | 88% |
Reaction Steps
Using a procedure analogous to that used to prepare 2D, 25C (277 mg, 0.67 mmol) was reacted with Intermediate 1 and glyoxylic acid monohydrate to afford 25D (460 mg, 88%) as a yellow solid. MS (ESI) m/z 787.00 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-073320ca7acf4d1e91ff2d3095cc14a1 |
| Source note | uspto-grants-2009_09 |