HuagongsheHuagongshe Chemistry Print Report · For research reference only
benzyl N-[2-(4-bromophenyl)ethyl]-N-methylcarbamate → 4-(2-((Benzyloxycarbonyl)(methyl)amino)ethyl)phenylboronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | benzyl N-[2-(4-bromophenyl)ethyl]-N-methylcarbamate | HCID 57842600 | — |
| Reactant | 4-(4-(3-Cyano-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenylboronic acid | HCID 57842684 | — |
| Product | 4-(2-((Benzyloxycarbonyl)(methyl)amino)ethyl)phenylboronic acid | HCID 57842578 | 74% |
Reaction Steps
Using a procedure analogous to that used to prepare 6D, 28C (1.14 g, 3.3 mmol) was 5′,5′-tetramethyl-[2,2′]bi[[1,3,2]dioxaborinanyl] to give 28D (760 mg, 74%) as a white solid. MS (ESI) m/z 313.97 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-b266c22af8eb437196afff097a9865af |
| Source note | uspto-grants-2009_09 |