HRID735585

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCS(=O)(=O)c1ccc(NC(=O)OCCc2ccc(C(Nc3ccc4c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc4c3)C(=O)O)cc2C)cc1C#N

HCID57842626

未命名化合物

结构：CCS(=O)(=O)c1ccc(NC(=O)N(C)CCc2ccc(C(Nc3ccc4c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc4c3)C(=O)O)cc2)cc1CN

HCID57842775

未命名化合物

PRODUCTS

生成物

HCID57842796

未命名化合物

收率 95%

PROCEDURE

实验过程

Using a procedure analogous to that used to prepare 25E, 31C (419 mg) was hydrogenated for 15 h to give 31D (400 mg, 95%) as a yellow glass. MS (ESI) m/z 792.43 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7214918fa7774726b6036a0d8f02d743
来源数据集: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07592331B2
来源说明: uspto-grants-2009_09

反应 SMILES

NCC1C=C(NC(=O)N(CCC2C=CC(C(NC3C=C4C(=CC=3)C(N(C(OC(C)(C)C)=O)C(OC(C)(C)C)=O)=NC=C4)C(O)=O)=CC=2)C)C=CC=1S(CC)(=O)=O.[C:57]([O:61][C:62]([N:64]([C:106]([O:108][C:109]([CH3:112])([CH3:111])[CH3:110])=[O:107])[C:65]1[C:74]2[C:69](=[CH:70][C:71]([NH:75][CH:76]([C:80]3[CH:85]=[CH:84][C:83]([CH2:86][CH2:87][O:88][C:89](=[O:104])[NH:90][C:91]4[CH:96]=[CH:95][C:94]([S:97]([CH2:100][CH3:101])(=[O:99])=[O:98])=[C:93]([C:102]#[N:103])[CH:92]=4)=[C:82]([CH3:105])[CH:81]=3)[C:77]([OH:79])=[O:78])=[CH:72][CH:73]=2)[CH:68]=[CH:67][N:66]=1)=[O:63])([CH3:60])([CH3:59])[CH3:58]>>[NH2:103][CH2:102][C:93]1[CH:92]=[C:91]([NH:90][C:89]([O:88][CH2:87][CH2:86][C:83]2[CH:84]=[CH:85][C:80]([CH:76]([NH:75][C:71]3[CH:70]=[C:69]4[C:74](=[CH:73][CH:72]=3)[C:65]([N:64]([C:106]([O:108][C:109]([CH3:112])([CH3:111])[CH3:110])=[O:107])[C:62]([O:61][C:57]([CH3:60])([CH3:58])[CH3:59])=[O:63])=[N:66][CH:67]=[CH:68]4)[C:77]([OH:79])=[O:78])=[CH:81][C:82]=2[CH3:105])=[O:104])[CH:96]=[CH:95][C:94]=1[S:97]([CH2:100][CH3:101])(=[O:99])=[O:98]