HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isocyanatobenzonitrile → HCID 57842652, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isocyanatobenzonitrile | HCID 2733315 | — |
| Reactant | HCID 57842797 | HCID 57842797 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57842652 | HCID 57842652 | 63% |
Reaction Steps
A solution of 36C (250 mg, 1.03 mmol) and 3-isocyanatobenzonitrile (164 mg, 1.03 mg) in CH2Cl2 (10 mL) was refluxed for 30 min. The solution was concentrated in vacuo and purified by flash chromatography (0% to 100% EtOAc in hexanes) to afford 36D (250 mg, 63%) as a yellow solid. MS (ESI) m/z 386.04/388.05 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-60cf76a558694e79a8903e2a178b4d3e |
| Source note | uspto-grants-2009_09 |