HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyldimethylsilyl chloride → (4-Bromo-2,6-dimethylphenethoxy)(tert-butyl)dimethylsilane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Reactant | (4-Bromo-2-ethylphenethoxy)(tert-butyl)dimethylsilane | HCID 57842587 | — |
| Reactant | 2-(4-Bromo-2,6-dimethylphenyl)ethanol | HCID 57842702 | — |
| Product | (4-Bromo-2,6-dimethylphenethoxy)(tert-butyl)dimethylsilane | HCID 57842569 | 80% |
Reaction Steps
Using a procedure analogous to that used to prepare 46A, 32B (3.0 g, 13.1 mmol) was reacted tert-butylchlorodimethylsilane to afford 50A (3.58 g, 80%) as a clear oil. 1H NMR (400 MHz, CDCl3) δ ppm −0.01 (s, 9 H) 2.30 (s, 6 H) 2.84 (t, J=7.70 Hz, 2 H) 3.66 (t, J=7.70 Hz, 2 H) 7.13 (s, 2 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-c9e70ac44d1c47ad93096ec1414efd30 |
| Source note | uspto-grants-2009_09 |