Trimethyl borate → 4-(2-(Tert-butyldimethylsilyloxy)ethyl)-3,5-dimethylphenylboronic acid

Participants

Reaction Steps

Using a procedure analogous to that used to prepare 46B, 50A (3.58 g, 10.5 mmol) was reacted trimethylborate to afford 50B (1.45 g, 45%) as a white solid. 1H NMR (400 MHz, MeOD) δ ppm −0.03 (s, 6 H) 0.85 (s, 9 H) 2.33 (s, 6 H) 2.92 (t, J=7.15 Hz, 2 H) 3.75 (t, J=7.42 Hz, 2 H) 7.20 (s, 2 H).

Provenance & Evidence