HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-(3-Cyano-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenylboronic acid → 4-(4-(3-Cyanophenylamino)-4-oxobutyl)-3-methylphenylboronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-(3-Cyano-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenylboronic acid | HCID 57842684 | — |
| Reactant | 4-(4-bromo-2-methylphenyl)-N-(3-cyanophenyl)butanamide | HCID 57842745 | — |
| Product | 4-(4-(3-Cyanophenylamino)-4-oxobutyl)-3-methylphenylboronic acid | HCID 57842818 | 56% |
Reaction Steps
Using a procedure analogous to that used to prepare 6D, 55C (200 mg, 0.56 mmol) was reacted with 5,5′,5′-tetramethyl-[2,2′]bi[[1,3,2]dioxaborinanyl] to give 55D (200 mg, 56%) as a solid. MS (ESI) m/z 323.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-7fcfeaecd452406ea14fd159fd828016 |
| Source note | uspto-grants-2009_09 |