HuagongsheHuagongshe Chemistry Print Report · For research reference only
9-Borabicyclo(3.3.1)nonane → 2-(4-Bromo-2-chlorophenyl)ethan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 9-Borabicyclo(3.3.1)nonane | HCID 78966 | — |
| Reactant | 4-Bromo-2-chloro-1-ethenylbenzene | HCID 57842713 | — |
| Reactant | 2-(4-Bromo-2-methylphenyl)ethanol | HCID 57842852 | — |
| Product | 2-(4-Bromo-2-chlorophenyl)ethan-1-ol | HCID 57842802 | 54% |
Reaction Steps
Using a procedure analogous to that used to prepare 30B, 61A (5 g, 23 mmol) was heated in a pressure vessel with 9-BBN at 100° C. for 10 h and worked up as in 30B to yield 61B (2.9 g, 54%) as an oil. 1H NMR (400 MHz, CDCl3) δ ppm 2.95 (t, J=6.59 Hz, 2 H) 3.85 (t, J=6.59 Hz, 2 H) 7.14 (d, J=7.91 Hz, 1 H) 7.33 (dd, J=8.13, 1.98 Hz, 1 H) 7.52 (d, J=2.20 Hz, 1 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-5934a5e8f54d4467b71a53eb70fc897d |
| Source note | uspto-grants-2009_09 |