反应详情

Using a procedure analogous to that used to prepare 30A, 62C (2 g, 6.1 mmol) was reacted with trimethyl(vinyl)silane in a pressure vessel at 160° C. for 1 h and worked up in a manner similar as in 30A to yield 62D (1.4 g, 88%) as an oil. 1H NMR (400 MHz, CDCl3) δ ppm 1.44 (t, J=7.03 Hz, 3 H) 4.02 (q, J=6.74 Hz, 2 H) 5.27 (d, J=10.99 Hz, 1 H) 5.74 (d, 1 H) 6.92-7.01 (m, 2 H) 7.04 (d, 1 H) 7.31 (d, J=7.91 Hz, 1 H).