HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glyoxylic acid, monohydrate → HCID 57842711, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glyoxylic acid, monohydrate | HCID 15620607 | — |
| Reactant | HCID 57842816 | HCID 57842816 | — |
| Reactant | tert-butyl N-(6-aminoisoquinolin-1-yl)-N-[(tert-butoxy)carbonyl]carbamate | HCID 58717298 | — |
| Product | HCID 57842711 | HCID 57842711 | 95% |
Reaction Steps
Using a procedure analogous to that used to prepare 2D, 64D (175 mg, 0.37 mmol) was reacted with Intermediate 1 and glyoxylic acid monohydrate to afford 65A (300 mg, 95%) as an oil. MS (ESI) m/z 848.5 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592331B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-189b4b30ccb44bb197bd87f9bdafe129 |
| Source note | uspto-grants-2009_09 |