HRID735704

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCC(O)Cc1ccc(C(Nc2ccc3c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc3c2)C(=O)NCc2cccc([N+](=O)[O-])c2)cc1

HCID57842791

未命名化合物

结构：CC(Cc1ccc(C(Nc2ccc3c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc3c2)C(=O)O)cc1)O[Si](C)(C)C(C)(C)C

HCID57842895

未命名化合物

PRODUCTS

生成物

结构：CC(Cc1ccc(C(Nc2ccc3c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc3c2)C(=O)NCc2cccc([N+](=O)[O-])c2)cc1)O[Si](C)(C)C(C)(C)C

HCID57842634

未命名化合物

收率 96%

PROCEDURE

实验过程

According to the procedure for the preparation of 70F, 77D (150 mg, 0.225 mmol) afforded 172 mg (96%) of 77E as a brown glass. MS (ESI) m/z 800.5 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b39f56d202b744399a8f854f7f8e5849
来源数据集: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07592331B2
来源说明: uspto-grants-2009_09

反应 SMILES

C(OC(N(C(OC(C)(C)C)=O)C1C2C(=CC(NC(C3C=CC(CC(O)CC)=CC=3)C([NH:23][CH2:24][C:25]3[CH:30]=[CH:29][CH:28]=[C:27]([N+:31]([O-:33])=[O:32])[CH:26]=3)=O)=CC=2)C=CN=1)=O)(C)(C)C.[C:52]([O:56][C:57]([N:59]([C:92]([O:94][C:95]([CH3:98])([CH3:97])[CH3:96])=[O:93])[C:60]1[C:69]2[C:64](=[CH:65][C:66]([NH:70][CH:71]([C:75]3[CH:80]=[CH:79][C:78]([CH2:81][CH:82]([O:84][Si:85]([C:88]([CH3:91])([CH3:90])[CH3:89])([CH3:87])[CH3:86])[CH3:83])=[CH:77][CH:76]=3)[C:72]([OH:74])=O)=[CH:67][CH:68]=2)[CH:63]=[CH:62][N:61]=1)=[O:58])([CH3:55])([CH3:54])[CH3:53]>>[C:52]([O:56][C:57]([N:59]([C:92]([O:94][C:95]([CH3:97])([CH3:96])[CH3:98])=[O:93])[C:60]1[C:69]2[C:68](=[CH:67][C:66]([NH:70][CH:71]([C:75]3[CH:76]=[CH:77][C:78]([CH2:81][CH:82]([O:84][Si:85]([C:88]([CH3:89])([CH3:91])[CH3:90])([CH3:87])[CH3:86])[CH3:83])=[CH:79][CH:80]=3)[C:72]([NH:23][CH2:24][C:25]3[CH:30]=[CH:29][CH:28]=[C:27]([N+:31]([O-:33])=[O:32])[CH:26]=3)=[O:74])=[CH:65][CH:64]=2)[CH:63]=[CH:62][N:61]=1)=[O:58])([CH3:53])([CH3:55])[CH3:54]