HRID735709

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCS(=O)(=O)c1ccc(NC(=O)COc2c(C)cc(B(O)O)cc2C)cc1CNC(=O)OCc1ccccc1

HCID57842628

未命名化合物

结构：CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nccc2cc(NC(C(=O)O)c3ccc(OCC(=O)Nc4cccc(CNC(=O)OCc5ccccc5)c4)cc3)ccc12

HCID57842637

未命名化合物

PRODUCTS

生成物

结构：CCS(=O)(=O)c1ccc(NC(=O)COc2c(C)cc(C(Nc3ccc4c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc4c3)C(=O)O)cc2C)cc1CNC(=O)OCc1ccccc1

HCID57842813

未命名化合物

收率 82%

PROCEDURE

实验过程

According to the procedure for the preparation of 66D, 79C (150 mg, 0.271 mmol) afforded 205 mg (82%) of 79D as an orange solid. MS (ESI) m/z 926.5 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-103da9add6d346f6a1b4057b9152478d
来源数据集: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07592331B2
来源说明: uspto-grants-2009_09

反应 SMILES

C(OC(NCC1C=C(NC(=O)COC2C=CC([CH:29]([NH:33][C:34]3[CH:35]=[C:36]4[C:41](=[CH:42][CH:43]=3)[C:40]([N:44]([C:52]([O:54][C:55]([CH3:58])([CH3:57])[CH3:56])=[O:53])[C:45]([O:47][C:48]([CH3:51])([CH3:50])[CH3:49])=[O:46])=[N:39][CH:38]=[CH:37]4)[C:30]([OH:32])=[O:31])=CC=2)C=CC=1)=O)C1C=CC=CC=1.[CH2:60]([O:67][C:68]([NH:70][CH2:71][C:72]1[CH:73]=[C:74]([NH:83][C:84](=[O:98])[CH2:85][O:86][C:87]2[C:92]([CH3:93])=[CH:91][C:90](B(O)O)=[CH:89][C:88]=2[CH3:97])[CH:75]=[CH:76][C:77]=1[S:78]([CH2:81][CH3:82])(=[O:80])=[O:79])=[O:69])[C:61]1[CH:66]=[CH:65][CH:64]=[CH:63][CH:62]=1>>[CH2:60]([O:67][C:68]([NH:70][CH2:71][C:72]1[CH:73]=[C:74]([NH:83][C:84](=[O:98])[CH2:85][O:86][C:87]2[C:92]([CH3:93])=[CH:91][C:90]([CH:29]([NH:33][C:34]3[CH:35]=[C:36]4[C:41](=[CH:42][CH:43]=3)[C:40]([N:44]([C:52]([O:54][C:55]([CH3:58])([CH3:57])[CH3:56])=[O:53])[C:45]([O:47][C:48]([CH3:51])([CH3:49])[CH3:50])=[O:46])=[N:39][CH:38]=[CH:37]4)[C:30]([OH:32])=[O:31])=[CH:89][C:88]=2[CH3:97])[CH:75]=[CH:76][C:77]=1[S:78]([CH2:81][CH3:82])(=[O:80])=[O:79])=[O:69])[C:61]1[CH:66]=[CH:65][CH:64]=[CH:63][CH:62]=1