Acetic Anhydride → HCID 57842763, compound

Participants

Reaction Steps

To a solution of 80A (500 mg, 1.50 mmol) in 5 mL CH2Cl2, were added TEA (0.229 mL, 1.65 mmol) and acetic anhydride (0.156 mL, 1.65 mmol). The mixture was stirred at rt for 2 h, then concentrated. The crude product was purified via flash chromatography (0 to 100% EtOAc in hexanes) to afford 80B (560 mg, 99%). MS (ESI) m/z 376.0 (M+H)+.

Provenance & Evidence