HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 4-(3-Tert-butoxy carbonyl phenyl)benzyl bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Tert-butyl-3-(4-tolyl)benzoate | HCID 18398672 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 4-(3-Tert-butoxy carbonyl phenyl)benzyl bromide | HCID 18398674 | 85.1% |
Reaction Steps
To a solution of tert-Butyl-3-(4-tolyl)benzoate (60 g, 0.22 mol) in CCl4 (800 mL) were added NBS (47.8 g, 0.268 mol) and benzoylperoxide (10 g) and the reaction mixture was refluxed overnight. Cooled to RT and filtered. The filtrate was concentrated to give 4-(3-tert-butoxy carbonyl phenyl)benzyl bromide (65 g, 84%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592477B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-e118c6b6916249c2947361c569b40e32 |
| Source note | uspto-grants-2009_09 |