HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorophenethylamine → N-[2-(3-chlorophenyl)ethyl]-N-[4-(3-undecyl-1,2,4-oxadiazol-5-yl)benzyl]amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorophenethylamine | HCID 139381 | — |
| Reactant | 4-(3-Undecyl-1,2,4-oxadiazol-5-yl)benzaldehyde | HCID 86598531 | — |
| Product | N-[2-(3-chlorophenyl)ethyl]-N-[4-(3-undecyl-1,2,4-oxadiazol-5-yl)benzyl]amine | HCID 67187804 | 62% |
Reaction Steps
The same procedure as employed in the preparation of Example 226 (step a) but using 4-(3-undecyl-1,2,4-oxadiazol-5-yl)benzaldehyde and [2-(3-chlorophenyl)ethyl]amine gave the title compound as a colorless oil (62%). 1H NMR (CDCl3, 300 MHz) δ 7.99 (d, J=8.3 Hz, 2H, 7.37 (d, J=8.3 Hz, 2H), 7.21-6.96 (m, 4H), 3.80 (s, 2H), 2.87-2.78 (m, 2H), 2.77-2.66 (m, 4H), 1.80-1.66 (m, 2H), 1.40-1.10 (m, 16H), 0.80 (t, J=7.2 Hz, 3H). M+(LC/MS(ESI)): 468.4. HPLC (Condition A), Rt: 5.1 min (HPLC purity: 99.1%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592477B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-8de7647bfcf64dd09935edfe5040faff |
| Source note | uspto-grants-2009_09 |