HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)benzylamine → N-[4-(3-octyl-1,2,4-oxadiazol-5-yl)benzyl]-N-[4-(trifluoromethyl)-benzyl]amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)benzylamine | HCID 76804 | — |
| Reactant | 4-(3-Octyl-1,2,4-oxadiazol-5-yl)benzaldehyde | HCID 86598532 | — |
| Product | N-[4-(3-octyl-1,2,4-oxadiazol-5-yl)benzyl]-N-[4-(trifluoromethyl)-benzyl]amine | HCID 67187477 | 49% |
Reaction Steps
The same procedure as employed in the preparation of Example 223 (step b) but using 4-(3-octyl-1,2,4-oxadiazol-5-yl)benzaldehyde and 4-(trifluoromethyl)benzylamine gave the title compound as a colorless oil (49%). M+(LC/MS(ESI)): 446.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592477B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-22c891e7fc5044c8a8cd164b953ac281 |
| Source note | uspto-grants-2009_09 |