Benzo(B)Thiophen-3-Ylmethylamine → HCID 67186360, compound

HRID 735967Notes

Reaction equation

HRID 735967 reaction equation
[CH2:1]([C:12]1[N:16]=[C:15]([C:17]2[CH:18]=[C:19]([CH:22]=[CH:23][CH:24]=2)[CH:20]=O)[O:14][N:13]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[S:25]1[C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][C:28]=2[C:27]([CH2:34][NH2:35])=[CH:26]1>>[S:25]1[C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][C:28]=2[C:27]([CH2:34][NH:35][CH2:20][C:19]2[CH:22]=[CH:23][CH:24]=[C:17]([C:15]3[O:14][N:13]=[C:12]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[N:16]=3)[CH:18]=2)=[CH:26]1

Participants

3

Reactant 2

HCID 2776347Benzo(B)Thiophen-3-YlmethylamineHCID 865985383-(3-Undecyl-1,2,4-oxadiazol-5-yl)benzaldehyde

Product 1

HCID 67186360HCID 67186360, compound

Procedure

The same procedure as employed in the preparation of Example 357 (step a) but using 3-(3-undecyl-1,2,4-oxadiazol-5-yl)benzaldehyde and 1-benzothien-3-ylmethylamine gave the title compound as an oil. M+(LC/MS(ESI)): 476.3. HPLC (Condition A), Rt: 4.79 min (HPLC purity: 86.7%).

Workup

  1. customThe same procedure as employed in the preparation of Example 357 (step a) but

Sources & evidence

ORD record
ord-5bbe3df91bb7490fb94bb02cba84bccf
Source dataset
uspto-grants-2009_09
Patent number
US07592477B2

Reaction notes

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