1,3-Benzodioxol-5-amine → HCID 67186501, compound

HRID 735981Notes

Reaction equation

HRID 735981 reaction equation
[CH2:1]([C:12]1[N:16]=[C:15]([C:17]2[CH:24]=[CH:23][C:20]([CH:21]=O)=[CH:19][CH:18]=2)[O:14][N:13]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[O:25]1[C:29]2[CH:30]=[CH:31][C:32]([NH2:34])=[CH:33][C:28]=2[O:27][CH2:26]1>>[O:25]1[C:29]2[CH:30]=[CH:31][C:32]([NH:34][CH2:21][C:20]3[CH:23]=[CH:24][C:17]([C:15]4[O:14][N:13]=[C:12]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[N:16]=4)=[CH:18][CH:19]=3)=[CH:33][C:28]=2[O:27][CH2:26]1

Participants

3

Reactant 2

HCID 843101,3-Benzodioxol-5-amineHCID 865985314-(3-Undecyl-1,2,4-oxadiazol-5-yl)benzaldehyde

Product 1

HCID 67186501HCID 67186501, compound

Procedure

The same procedure as employed in the preparation of Example 357 (step a) but using 4-(3-undecyl-1,2,4-oxadiazol-5-yl)benzaldehyde and 1,3-benzodioxol-5-ylamine gave the title compound as an oil. HPLC (Condition A), Rt: 5.15 min (HPLC purity: 97.2%).

Workup

  1. customThe same procedure as employed in the preparation of Example 357 (step a) but

Sources & evidence

ORD record
ord-006a6c194e4848f18ff1ad2af7a812dc
Source dataset
uspto-grants-2009_09
Patent number
US07592477B2

Reaction notes

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