p-(Octyloxy)benzaldehyde → HCID 67186975, compound

HRID 736002Notes

Reaction equation

HRID 736002 reaction equation
[CH2:1]([O:9][C:10]1[CH:17]=[CH:16][C:13]([CH:14]=O)=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[Cl:18][C:19]1[CH:20]=[C:21]([CH2:26][CH2:27][NH2:28])[CH:22]=[CH:23][C:24]=1[Cl:25]>>[Cl:18][C:19]1[CH:20]=[C:21]([CH2:26][CH2:27][NH:28][CH2:14][C:13]2[CH:16]=[CH:17][C:10]([O:9][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])=[CH:11][CH:12]=2)[CH:22]=[CH:23][C:24]=1[Cl:25]

Participants

3

Reactant 2

HCID 90358p-(Octyloxy)benzaldehydeHCID 2179583,4-Dichlorophenethylamine

Product 1

HCID 67186975HCID 67186975, compound

Procedure

The same procedure as employed in the preparation of Example 394 (step b) but using 4-(octyloxy)benzaldehyde and 2-(3,4-dichlorophenyl)ethylamine gave the title compound as an oil. HPLC (Condition A), Rt: 4.69 min (HPLC purity: 71.8%).

Workup

  1. customThe same procedure as employed in the preparation of Example 394 (step b)

Sources & evidence

ORD record
ord-325b83c3da084b9bb2b99cb0a91dd792
Source dataset
uspto-grants-2009_09
Patent number
US07592477B2

Reaction notes

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