4-Fluorobenzoyl chloride → HCID 57559107, compound

HRID 736058Notes

Reaction equation

HRID 736058 reaction equation
[F:1][C:2]1[CH:10]=[CH:9][C:8]2[NH:7][C:6]3[C:11]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:12][NH:13][CH2:14][CH2:15][C:5]=3[C:4]=2[CH:3]=1.[F:21][C:22]1[CH:30]=[CH:29][C:25]([C:26](Cl)=[O:27])=[CH:24][CH:23]=1>>[F:1][C:2]1[CH:10]=[CH:9][C:8]2[NH:7][C:6]3[C:11]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:12][N:13]([C:26](=[O:27])[C:25]4[CH:29]=[CH:30][C:22]([F:21])=[CH:23][CH:24]=4)[CH2:14][CH2:15][C:5]=3[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 66640204Ethyl 9-fluoro-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate

Product 1

HCID 57559107HCID 57559107, compound

Procedure

The title compound was prepared in a manner similar to that described in Example 2 by using ethyl 9-fluoro-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate and 4-fluorobenzoyl chloride; 1H-NMR (CDCl3): δ 10.57 (1H, br s), 8.04 (1H, s), 7.62 (2H, dd), 7.29 (1H, m), 7.16 (3H, m), 6.95 (1H, m), 4.24 (4H, m), 3.20 (2H, m), 1.22 (3H, t); MS (ES): 397 (MH+).

Sources & evidence

ORD record
ord-08f6ec70d8c545889a82051dc57f0172
Source dataset
uspto-grants-2009_09
Patent number
US07595311B2

Reaction notes

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