4-Fluorobenzoyl chloride → HCID 57559125, compound

HRID 736083Notes

Reaction equation

HRID 736083 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:12]2[NH:13][C:14]3[CH:15]=[C:16]([N+:20]([O-:22])=[O:21])[CH:17]=[CH:18][C:19]=3[C:11]=2[CH2:10][CH2:9][NH:8][CH:7]=1)=[O:5])[CH3:2].[F:23][C:24]1[CH:32]=[CH:31][C:27]([C:28](Cl)=[O:29])=[CH:26][CH:25]=1>>[CH2:1]([O:3][C:4]([C:6]1[C:12]2[NH:13][C:14]3[CH:15]=[C:16]([N+:20]([O-:22])=[O:21])[CH:17]=[CH:18][C:19]=3[C:11]=2[CH2:10][CH2:9][N:8]([C:28](=[O:29])[C:27]2[CH:31]=[CH:32][C:24]([F:23])=[CH:25][CH:26]=2)[CH:7]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 666402658-Nitro-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylic acid ethyl ester

Product 1

HCID 57559125HCID 57559125, compound

Procedure

The title compound was prepared in a manner similar to that described in Example 2A by using 8-nitro-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylic acid ethyl ester and 4-fluorobenzoyl chloride; MS (ES): 424 (MH+).

Sources & evidence

ORD record
ord-e235e5191a864cdf8013f053d983f59f
Source dataset
uspto-grants-2009_09
Patent number
US07595311B2

Reaction notes

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