HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropyl iodide → 2-Chloro-5-(propane-2-sulfonyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropyl iodide | HCID 6362 | — |
| Reactant | 2-Chloro-5-(methylsulphonyl)benzoic acid | HCID 2329132 | — |
| Reactant | 2-Chloro-5-sulfino-benzoic acid | HCID 15112904 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 2-Chloro-5-(propane-2-sulfonyl)benzoic acid | HCID 43140999 | 42% |
Reaction Steps
The title compound was synthesised according to the procedure described for the synthesis of 2-Chloro-5-methanesulfonyl-benzoic acid from 2-Chloro-5-sulfino-benzoic acid and 2-iodopropane in 20 ml isopropanol/20 ml water and obtained in 42% yield. MS (m/e): 261.1 (MH−, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07595314B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-97472c64e94d4f6dbd909ca05fa4f7b1 |
| Source note | uspto-grants-2009_09 |