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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 73614Generated: October 29, 2026

(4aS,8aS)-1-benzyl-4-(phenylamino)octahydroquinolin-4a(2H)-ol → HCID 68154084, compound

https://huagongshe.com/reaction/73614

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4aS,8aS)-1-benzyl-4-(phenylamino)octahydroquinolin-4a(2H)-olHCID 52911548—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 68154084HCID 68154084—

Reaction Conditions

Temperature60 °C

Reaction Steps

To a mixture of (4aS,8aS)-1-benzyl-4-(phenylamino)octahydroquinolin-4a(2H)-ol (0.280 g, 0.832 mmol) in MeOH (5 mL) was added NH4COOH (0.840 g, 13.3 mmol) and 10% Pd/C (0.280 g). The resulting mixture was heated at 60° C. for several hours. The reaction was cooled to rt, filtered through a syringe filter, washed with EtOH, and concentrated to give the title compound. LRMS M+H calc'd: 247.34. found 247.34

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08829196B2
Source datasetuspto-grants-2014_09
ORD IDord-4f198c0a3a474dfe812baf3eda919d30
Source noteuspto-grants-2014_09