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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 736140Generated: October 25, 2026

Cyclopropanemethanamine → 2-Chloro-5-(cyclopropylmethyl-sulfamoyl)-benzoic acid

https://huagongshe.com/reaction/736140

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanemethanamineHCID 75646—
ReactantBenzoic acid, 2-chloro-5-[(methylamino)sulfonyl]-HCID 111724—
Reactant2-Chloro-5-sulfino-benzoic acidHCID 15112904—
Product2-Chloro-5-(cyclopropylmethyl-sulfamoyl)-benzoic acidHCID 2903558081%

Reaction Steps

The title compound was synthesised according to the procedure described for 2-Chloro-5-methylsulfamoyl-benzoic acid from 2-Chloro-5-sulfino-benzoic acid and cyclopropylmethylamine and obtained in 81% yield. MS (m/e): 288.0 (MH−, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07595314B2
Source datasetuspto-grants-2009_09
ORD IDord-bbdb1b49bc5347ee88204033eb6120d0
Source noteuspto-grants-2009_09