化工社化工社 化学情報印刷レポート · 研究参考用
Pyrrolidine → 5-Methylsulfamoyl-2-pyrrolidin-1-yl-benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pyrrolidine | HCID 31268 | — |
| 反応物 | Benzoic acid, 2-chloro-5-[(methylamino)sulfonyl]- | HCID 111724 | — |
| 反応物 | 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid | HCID 59793489 | — |
| 生成物 | 5-Methylsulfamoyl-2-pyrrolidin-1-yl-benzoic acid | HCID 45319690 | 45% |
反応手順
The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid from 2-Chloro-5-methylsulfamoyl-benzoic acid and pyrrolidine and obtained in 45% yield. MS (m/e): 283.1 (MH−, 100%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07595314B2 |
| 出典データセット | uspto-grants-2009_09 |
| ORD ID | ord-08aba786e9fb4311b4980c039ef2c668 |
| 出典メモ | uspto-grants-2009_09 |