HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 5-(Cyclopropylmethyl-sulfamoyl)-2-pyrrolidin-1-yl-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 2-Chloro-5-(cyclopropylmethyl-sulfamoyl)-benzoic acid | HCID 29035580 | — |
| Reactant | 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid | HCID 59793489 | — |
| Product | 5-(Cyclopropylmethyl-sulfamoyl)-2-pyrrolidin-1-yl-benzoic acid | HCID 59793495 | 38% |
Reaction Steps
The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid from 2-Chloro-5-(cyclopropylmethyl-sulfamoyl)-benzoic acid and pyrrolidine and obtained in 38% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07595314B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-4ca8d71b6dbb4d62b9c25dc812bff8fb |
| Source note | uspto-grants-2009_09 |