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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 736152Generated: October 25, 2026

Morpholine → 5-Ethanesulfonyl-2-morpholin-4-yl-benzoic acid

https://huagongshe.com/reaction/736152

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant2-Chloro-5-(ethanesulfonyl)benzoic acidHCID 43140992—
Reactant5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acidHCID 59793489—
Product5-Ethanesulfonyl-2-morpholin-4-yl-benzoic acidHCID 5979366877%

Reaction Steps

The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid from 2-Chloro-5-(ethane-2-sulfonyl)-benzoic acid and morpholine and obtained in 77% yield. MS (m/e): 298.2 (MH−, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07595314B2
Source datasetuspto-grants-2009_09
ORD IDord-8b8c004bda754917bb94f8904f8d4e62
Source noteuspto-grants-2009_09