1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone → 3-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-chloro-N,N-dimethyl-benzenesulfonamide

Participants

Role	Name	HCID	Charge
Reactant	1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone	HCID 685610	—
Reactant	2-Chloro-5-(dimethylsulfamoyl)benzoic acid	HCID 2324784	—
Product	3-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-chloro-N,N-dimethyl-benzenesulfonamide	HCID 41770750	—

Reaction Steps

The title compound was prepared according to the procedure described for example K/step 2 from 1-(3-Fluoro-4-piperazin-1-yl-phenyl)-ethanone and 2-Chloro-5-dimethylsulfamoyl-benzoic acid (CAS: 37088-27-0; BE 620741) (64%, light yellow foam, MS (m/e): 468.1 (M+H+, 100%)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07595314B2
Source dataset	uspto-grants-2009_09
ORD ID	ord-e3bd38ac04514d1bb4560b659b01cf10
Source note	uspto-grants-2009_09