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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 736178Generated: October 25, 2026

1-(4-(Methylsulfonyl)phenyl)piperazine → (4-(4-(Methylsulfonyl)phenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone

https://huagongshe.com/reaction/736178

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-(Methylsulfonyl)phenyl)piperazineHCID 735904—
Reactant2-Morpholin-4-yl-5-nitro-benzoyl chlorideHCID 17274153—
Product(4-(4-(Methylsulfonyl)phenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanoneHCID 44580303—

Reaction Steps

The title compound was prepared according to the procedure described for example 46 from 1-(4-Methanesulfonyl-phenyl)-piperazine and 2-Morpholin-4-yl-5-nitro-benzoyl chloride (76%, yellow solid, MS (m/e): 475.1 (M+H, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07595314B2
Source datasetuspto-grants-2009_09
ORD IDord-bb011b520aa642a79b4126487123473a
Source noteuspto-grants-2009_09