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HRID 736220作成日：2026年10月25日

1-(4-(Trifluoromethyl)phenyl)piperazine → 3,4-Difluoro-N-methyl-5-[4-(4-trifluoromethyl-phenyl)-piperazine-1-carbonyl]-benzenesulfonamide

https://huagongshe.com/reaction/736220

反応式

関与物質

役割名称HCID仕込み量
反応物1-(4-(Trifluoromethyl)phenyl)piperazineHCID 121718—
反応物2,3-Difluoro-5-methylsulfamoyl-benzoic acidHCID 68839247—
生成物3,4-Difluoro-N-methyl-5-[4-(4-trifluoromethyl-phenyl)-piperazine-1-carbonyl]-benzenesulfonamideHCID 59793564—

反応手順

The title compound was prepared in analogy to Example BO by reaction of 2,3-Difluoro-5-methylsulfamoyl-benzoic acid and 1-(4-trifluoromethylphenyl)piperazine (ABCR F07741NB, [30459-17-7]) to yield the title compound as a light yellow amorpous solid. (m/e): 462.1 (M−H, 100%).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07595314B2
出典データセットuspto-grants-2009_09
ORD IDord-e3ccc4d7b913426cadc3d7e53e7f47df
出典メモuspto-grants-2009_09