HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-Fluoro-4-(methylsulfonyl)phenyl]piperazine → [4-(2-Fluoro-4-methanesulfonyl-phenyl)-piperazin-1-yl]-(2-iodo-5-methanesulfonyl-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-Fluoro-4-(methylsulfonyl)phenyl]piperazine | HCID 2782730 | — |
| Reactant | 2-Iodo-5-methanesulfonyl-benzoic acid | HCID 57445281 | — |
| Product | [4-(2-Fluoro-4-methanesulfonyl-phenyl)-piperazin-1-yl]-(2-iodo-5-methanesulfonyl-phenyl)-methanone | HCID 59793539 | — |
Reaction Steps
Example CM was prepared in analogy to Example 123 from 2-Iodo-5-methanesulfonyl-benzoic acid (example BQ) and 1-(2-Fluoro-4-methanesulfonyl-phenyl)-piperazine (commercial). MS (m/e): 567.0 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07595314B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-c259a8e28cb445668eb3e2a4ef378374 |
| Source note | uspto-grants-2009_09 |