HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone → [5-Methanesulfonyl-2-(4-methyl-imidazol-1-yl)-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 59793691 | — |
| Reactant | HCID 178418800 | HCID 178418800 | — |
| Product | [5-Methanesulfonyl-2-(4-methyl-imidazol-1-yl)-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 68843179 | 32% |
Reaction Steps
The title compound was prepared according to the procedure described for example 199 from (2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone (compound CK) and 4-Methyl-1H-imidazole (32% yield, white solid, MS (m/e): 493.4 (M+H, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07595314B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-bad3c885f84d4b139ee7dedc7afb6fea |
| Source note | uspto-grants-2009_09 |