反应详情

The product from Example 42B (0.103 g) in EtOH (0.7 mL) and MeCN (2.1 mL) was treated with CsF (72 mg, 0.47 mmol), stirred for 5 minutes, diluted with saturated NH4Cl (7 mL), and extracted with CH2Cl2 (2×7 mL). The organic extract was dried (Na2SO4), filtered, and the filtrate concentrated under reduced pressure. The residue was purified by flash chromatography (7% ethyl acetate in hexanes) to provide the title compound.

1. extractionextracted with CH2Cl2 (2×7 mL)
2. extractionThe organic extract
3. dry with materialwas dried (Na2SO4)
4. filtrationfiltered
5. concentrationthe filtrate concentrated under reduced pressure
6. customThe residue was purified by flash chromatography (7% ethyl acetate in hexanes)